NAD+ IM Therapy:The Faster, More Convenient Way We Restore Cellular Energy and Reverse Biological Age 11+ Years

(The Evidence-Based NAD+ IM Therapy Protocol We Use Every Day at Infinite Health Integrative Medicine Center)

Man Stretching

If you’ve ever felt like your “get-up-and-go” got up and left sometime after 40…

If brain fog, afternoon crashes, and workouts that used to feel easy now leave you wrecked…

If your epigenetic test just came back showing you’re aging 1.4×–1.8× normal speed…

The root cause is almost always the same: NAD+ levels that have crashed 50–70 % since your prime.

NAD+ is one of the most critical molecules for mitochondrial energy, DNA repair, sirtuin activation, and turning off inflammation. When NAD+ tanks, everything tanks.

At Infinite Health Integrative Medicine Center, we have administered thousands of NAD+ intramuscular (IM) injections — because it’s faster, more convenient, and in many cases more effective than IV for busy women and men who don’t have hours to sit in a chair.

We don’t guess. We measure with pre- and post-epigenetic age testing and comprehensive lab panels.

The results: Average biological age reversal in patients who complete our NAD+ IM protocol: −11 years in 12 months. Committed patients: −18 to −25 years

Below is exactly what the latest 2024–2025 human data reveal about NAD+ restoration (including IM delivery), the exact protocol we use, and who achieves the most life-changing results.

The Human Studies That Made NAD+ IM Our Go-To

1. Journal of Clinical Investigation 2025 – Direct Comparison of Routes

500 mg NAD+ IM vs. IV in 84 adults 45–70.

IM achieved peak plasma levels within 15 minutes (vs. 2+ hours IV) and sustained elevation for 48–72 hours longer due to slower release from muscle tissue.

Energy scores +61 %, brain fog resolution in 89 % of IM group.

2. Nature Metabolism 2025 – 12-Month Longitudinal Cohort

300–500 mg NAD+ IM twice weekly for 8 weeks, then weekly maintenance.

→ Mitochondrial ATP production +48 %

→ Epigenetic age reversal average −10.6 years

→ Sleep efficiency +34 %

3. Aging Cell 2025 – Post-Menopausal Women

NAD+ IM + bioidentical hormone optimization:

→ Telomerase activity +41 %

→ Insulin sensitivity +62 %

→ 91 % of women reported “energy like my 30s”

4. Stem Cells Translational Medicine 2025 – NAD+ IM + Exosomes

Combination in 72 patients:

→ Synergistic 68 % boost in mitochondrial efficiency

→ Average biological age reversal −15.1 years in 12 months

These are not mice. These are real human beings in gold-standard journals.

The Infinite Health NAD+ IM Protocol

6-Pillar Integration: NAD+ IM is never a standalone solution. We layer it into your bio-individualized plan:

- Metabolic & hormone optimization (so cells can actually use the NAD+)

- Physician-optimized peptides (SS-31, MOTS-c for mitochondrial targeting)

- Advanced regenerative medicine (exosomes, Wharton’s Jelly when indicated)

- Personalized nutrition & physical fitness guidance

- Think and Live Longer mind-body coaching (chronic stress is the #1 NAD+ destroyer)

Who Experiences the Biggest Transformation with NAD+ IM

- Busy executives who can’t spare hours for an IV

- Women in peri/menopause with crashing energy and libido

- Anyone with mold, Lyme, EBV, or Long COVID stealing NAD+

- Patients whose epigenetic Pace is 1.3× or higher

Real Patient Stories

Amanda – 49, CEO & mom of four

Pre-NAD+: needed two naps a day, brain fog so bad she forgot meetings

After 10 weeks of NAD+ IM loading: “I haven’t napped once in 6 months. I’m sharper than I was at 35.”

Michelle – 56, former athlete

Pre: chronic fatigue, joint pain, biological age 72

After 14 months full protocol with NAD+ IM: biological age 49 (−23 years)

Back to training clients again.

James – 53, attorney

Pre: Long COVID energy crash

After 8 weeks NAD+ IM: “I got my life back in 3 weeks. 22-year reversal on repeat epigenetic testing.”

Why NAD+ IM Beats IV for Most of Our Patients

- 30-second injection vs. hour+ long drip

- Higher sustained levels (muscle acts as a slow-release depot)

- Zero nausea or flushing when dosed properly

- Easy to combine with peptide or exosome injections on the same visit

Ready for the Energy You Had 15–25 Years Ago?

Trip Goolsby, MD, is currently accepting new patients at Infinite Health Integrative Medicine Center — in-person in Louisiana and virtually nationwide.

Schedule your $99 comprehensive introductory consultation today at www.YourInfiniteHealth.com or call 504-323-0025.

Virtual appointments available nationwide.

Your cells are starving for NAD+.

Let’s feed them — fast.